В. Ф. Беженарь [и др.] // Журнал акушерства и женских болезней. 2003. Том LII, вып. С. 35 47


© Е.A. Vlasyants, M.E. Yevseyeva, 2009



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© Е.A. Vlasyants, M.E. Yevseyeva, 2009


UDC 616.12-008.318:612.751.3:616-007.17

Vlasyants E.A., Yevseyeva M.E. Influence of heart connective tissue dysplasia and diastolic left ventricle dysfunction on arrhythmic syndrome in ischemic heart disease // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. – № 1 (30). – Р. 155-158.

1Stavropol State Medical Academy, Russia, 355014, Stavropol, Mira str., 310. Tel. (8653)35-24-37. E-mail: postmaster@stgma.ru; official site: http://www.stgma.ru

2Stavropol territorial clinical cardiologic dispensary, Russia, Stavropol, Prigorodnaya str., 224а, tel.: +7 (8652) 36 51 48 fax: +7 (8652) 36 59 90

Summary: 130 able-bodied persons with ischemic heart disease, exertional angina pectoris FK II-III on the background of GB II-III degree were examined for rhythm disorders depending on the presence of HCTD and LV DD as well. Three groups were distinguished: the first group with IHD-HCTD-LV DD (41 patients); the second group: IHD+HCTD+LV DD (50 patients); the third group: IHD+LV DD-HCTD (39 patients). 24-hour ECG monitoring was performed with quantitative extrasystole and other arrhythmias determination, and also ECHOCG was taken for revealing insignificant heart abnormalities and determination of parameters of transmural flow. Phenotipical analysis of external morphoplasia was done. Ventricular extrasystole manifestation, including bigerminals, as well as paroxysmal ZT and paroxysmal MA turned out to be higher in patients with IHD on the background DSTS and DD LZ comparing with patients suffering IHD in an isolated form.

Key words: heart connective tissue dysplasia, left ventricle diastolic dysfunction, ischemic heart disease, arrhythmic syndrome.

References:

1. Антюфьев В.Ф. Гемодинамика неритмично работающего сердца (механизмы сердечной недостаточности при аритмиях). – Екатеринбург, 1995. – 327 с.

2. Антропометрический скрининг при массовых профилактических осмотрах: Метод. реком / под ред. И.М. Воронцова. - Л., 1991.

3. Бокерия Л.А. Тахиаритмия. - М.:Медицина, 1989. – 295 с.

4. Бунак В.В. Антропометрия. - М.: Учпедгиз, 1941.

5. Глезер М.Г., Орлов Л.Л. Тактика лечения больных с нарушениями ритма сердца // Клиническая медицина. - 1995.-№ 4.-С.13-17.

6. Диастолическая сердечная недостаточность. (Секционное заседание) // Сердечная недостаточность. - № 1. – С. 58-60.

7. Дощицин В.Л. Диагностика и лечение аритмий сердца. - М.: Медицина, 1993. - 202 с.

8. Кушаковский М.С. Аритмии сердца. - СПб.: Фолиант, 1998. – 640 с.

9. Мазур Н.А. Внезапная смерть больных ишемической болезнью сердца. - М.: Медицина, 1985. - 190 с.

10. Малая Л.Т., Латогуз И.К., Микляев И.Ю., Визир А.Д. Ритмы сердца. - Харьков.: Основа, 1993. – 665 с.

11. Мыслицкая Г.В., Новиков В.И., Узилевская Р.А. Нарушения сердечного ритма при синдроме пролапса митрального клапана и их лечение // Кардиология. - 1986. - № 8. - С. 49-53.

12. Сметнев А.С., Гроссу А.А., Шевченко Н.М. Диагностика и лечение нарушений ритма сердца. - Кишинев, 1990. – 202 с.

13. Янушкевичус З.И., Бредикис Ю.Ю., Лукошявичуте А.И., Забела П.В. Нарушения ритма и проводимости сердца. - М., 1984. – 116 с.

14. Moss A.J. Identification of patient at increased risk for potentially malignant arrhythmias // Cardiovasc. Drugs Ther. - 1990. - Vol. 4, № 3. – P. 33-52.

15. Sakomoto T. Syndrom of mitral valve prolaps: past, present and prospects // J. Cardiogr.Suppl. - 1986. - Vol. 11. – P. 5-17.

16. Prolapsul valvei mitrale. Studiu ecocardiografic a 456 de casuri /Apetrei E., Coman I., Alexandru D. et al. // Med. Interna. – 1990. – Vol. 42, № 1. - P. 69-77.



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© V.G. Lychev, V.V. Usinin, A.V. Andriyenko, T.M. Samoilova, 2009


UDC 616.12-008.331.1:616.15

Lychev V.G.1, Usinin V.V.1, Andriyenko A.V.1, Samoilova T.M.2 Microcirculation and blood rheology rhythm study in patients with essential hypertension // Herald of the Mechnikov Saint-Petersburg State Medical Academy. – 2009. – № 1 (30). – Р. С. 158-161.

1State educational establishment for higher professional training “Altai State Medical University”, Russia, 656099, Barnaul, Lenin prospect, 40, (3852) 405657, gosp_therapy@mail.ru

2 Municipal institution of public health “Municipal hospital № 4”. Address: Russia, 656050, Barnaul, Yurin str., 166-а. Tel.: 41-97-93 (reception room), fax 41-97-71.

Summary: With the purpose of study microcirculation, haemorheology and hemostasis at the patients with essential arterial hypertension (AH), we defined laser doppler fluometry (LDF) parameters, haemorheology and haemocoagulation parameters. At observation 36 patients were found, that the laser doppler perfusion (LDP) index at the patients was 18,18±0,66 (healthy group - 13,79±0,79 p<0,05), coefficient of variation - 10,42±0,55% (healthy group - 18,48±0,91%, p<0,05). Is found, that at the patients with AH is present microrheological disbalance, conjugated with changes of parameters haemorheology and hemostasis. At the correction of blood pressure the parameters of haemorheology and hemostasis are normalized. Correction parameters of microcirculation in short-term observation is incomplete. LDP index reaches normative values, and the value of perfusion rhythms and degree of a diversification microcirculation rhythm completely is not normalized. Non-invasive LDF method allows to supervise regeneration of parameters microcirculation at treatment of an essential arterial hypertension.

Key words: laser doppler fluometry, LDF, haemorheology, hemostasis, arterial hypertension.

References:

1. Козлов В.И., Мач Э.С., Литвин Ф.Б. и соавт. Метод лазерной допплеровской флоуметрии: Пособие для врачей. - М., 2001. - 24 с.

2. Лазерная допплеровская флоуметрия микроциркуляции крови: Руководство для врачей / под ред. А.И. Крупаткина, В.В. Сидорова. – М.: «Медицина», 2005. - 256 с.



3. Лычев В.Г. Диагностика и лечение диссеминированного внутрисосудистого свертывания крови. - М.: НГМА, 2001. – 192 с.

4. Микроциркуляция в кардиологии / под ред. В.И. Маколкина. - М.: «Визарт», 2004. – 135 с.

Information about the authors:

Lychev Valery Germanovich, M.D., Professor, head of the department of Hospital and Polyclinic Therapy with the course of Occupational Diseases and Endocrinology. Russia, 656038, Altai area, Barnaul, Chkalov str., 65а, apt., 12, tel.: (3852) 40-56-57, E-mail: gosp_therapy@mail.ru

Usynin Vladimir Valeriyevich, Candidate of Medical Sciences, Assistant-Professor of the department of Hospital and Policlinic Therapy with the course of Occupational Diseases and Endocrinology. Russia, 656033, Altai area, Barnaul, Molodezhnaya str., 41, apt. 125, tel.: (3852) 62-44-66, е-mail: usynin@alt.ru .

Andrienko Aleksey Vladimirovich, Candidate of Medical Sciences, assistant of the department of Hospital and Polyclinic Therapy with the course of Occupational Diseases and Endocrinology. Russia, 656050 Altai area, Barnaul, Solntsev str.,7, apt. 42, tel.: (3852) 40-56-57, е-mail: gosp_therapy@mail.ru .

Samoilova Naniyana Maevna, hospital doctor of the Therapy department, Municipal institution of public health Municipal hospital №4. Russia, 656041 Altai area, Barnaul, Yurin str., 66а, apt., 4, tel.: (3852) 41-23-68, е-mail: gosp_therapy@mail.ru



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